Please cite:
Dimitra Karagkouni, Maria D. Paraskevopoulou, Serafeim Chatzopoulos, Ioannis S. Vlachos, Spyros Tastsoglou, Ilias Kanellos, Dimitris Papadimitriou, Ioannis Kavakiotis, Sofia Maniou, Giorgos Skoufos, Thanasis Vergoulis, Theodore Dalamagas, Artemis G. Hatzigeorgiou; DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA–gene interactions, Nucleic Acids Research, gkx1141, https://doi.org/10.1093/nar/gkx1141
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hsa-let-7b-5p


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Filters
Interactions: 6357, Experiments: (low: , high: , unknown: ) Cell lines: , Tissues: , Publications:
Gene name miRNA name Experiments
throughput
Publications Cell lines Tissues Pred. Score
CYP2J2 hsa-let-7b-5p low: 15 high: 0 1 6 7 -
Low-throughput experiments (9 positive, 6 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Fuqiong Chen et al. 2012 RP RP Lung SKMES1 SKMES1 N/A
Location Method Result Regulation Validation Type Source
chr1:59893483-59893506 Luciferase Reporter Assay POSITIVE DIRECT TarBase 7.0
chr1:59892911-59893678 Luciferase Reporter Assay POSITIVE DIRECT TarBase 7.0
chr1:59893519-59893540 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 7.0
chr1:59893506-59893525 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 7.0
chr1:59893435-59893464 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 7.0
chr1:59893325-59893349 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 7.0
chr1:59893311-59893341 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Tongue TCA8113 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot POSITIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Lung SKMES1 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot POSITIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Lung Cancerous Tissues N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot POSITIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 qP Breast Cancerous Tissues N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN qPCR NEGATIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Mammary Gland MDAMB435 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot POSITIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Cervix HELA N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot POSITIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 RP Mammary Gland MDAMB435 MDAMB435 N/A
Location Method Result Regulation Validation Type Source
chr1:59892911-59893678 Luciferase Reporter Assay POSITIVE DIRECT TarBase 7.0
Fuqiong Chen et al. 2012 RP Liver HEPG2 HEPG2 N/A
Location Method Result Regulation Validation Type Source
chr1:59892911-59893678 Luciferase Reporter Assay POSITIVE DIRECT TarBase 7.0
HMGA2 hsa-let-7b-5p low: 2 high: 20 9 8 5 -
Low-throughput experiments (2 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Alajez Nehad M. et al. 2012 RP Pharynx FADU HEK293 N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
Guo L. et al. 2013 RP Mammary Gland MDAMB231 MCF7 N/A
Location Method Result Regulation Validation Type Source
chr12:65965688-65965862 Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
High-throughput experiments (20 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Grosswendt S et al. 2014 IP Kidney HEK293 N/A N/A
Location Method Result Regulation Validation Type Source
chr12:65965794-65965820 Chimeric fragments POSITIVE DIRECT TarBase 8.0
Selbach M et al. 2008 MA Cervix HELA N/A 8hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays POSITIVE INDIRECT TarBase 8.0
Selbach M et al. 2008 MA Cervix HELA N/A 32hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays POSITIVE INDIRECT TarBase 8.0
Whisnant Adam W et al. 2013 IP Cervix TZMBL N/A shRNAs against HIV-1
Location Method Result Regulation Validation Type Source
chr12:65964534-65964554 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Whisnant Adam W et al. 2013 IP Cervix TZMBL N/A N/A
Location Method Result Regulation Validation Type Source
chr12:65964534-65964554 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Sebastian Memczak et al. 2013 IP Kidney HEK293 N/A N/A
Location Method Result Regulation Validation Type Source
chr12:65964534-65964554 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Kishore S et al. 2011 IP Kidney HEK293 N/A mild MNase digestion
Location Method Result Regulation Validation Type Source
chr12:65965814-65965839 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964894-65964917 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964534-65964554 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964534-65964554 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964383-65964405 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65963296-65963320 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Karginov FV et al. 2013 IP Kidney 293S N/A treatment: arsenite
Location Method Result Regulation Validation Type Source
chr12:65964534-65964554 HITS-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964383-65964405 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Balakrishnan I et al. 2014 IP Bone Marrow HS5 N/A N/A
Location Method Result Regulation Validation Type Source
chr12:65965814-65965839 HITS-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964939-65964966 HITS-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964534-65964554 HITS-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964383-65964405 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Balakrishnan I et al. 2014 IP Bone Marrow HS27A N/A N/A
Location Method Result Regulation Validation Type Source
chr12:65964534-65964554 HITS-CLIP POSITIVE DIRECT TarBase 7.0
chr12:65964383-65964405 HITS-CLIP POSITIVE DIRECT TarBase 7.0
BAX hsa-let-7b-5p low: 2 high: 2 2 3 3 -
Low-throughput experiments (0 positive, 2 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Fuqiong Chen et al. 2012 WB Mammary Gland MDAMB435 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Heart H9C2 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
High-throughput experiments (0 positive, 2 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Selbach M et al. 2008 MA Cervix HELA N/A 8hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays NEGATIVE INDIRECT TarBase 8.0
Selbach M et al. 2008 MA Cervix HELA N/A 32hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays NEGATIVE INDIRECT TarBase 8.0
CTHRC1 hsa-let-7b-5p low: 2 high: 2 2 3 3 -
Low-throughput experiments (2 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Yu J. et al. 2015 RP Stomach AGS AGS N/A
Location Method Result Regulation Validation Type Source
chr8:103382605-103382627 Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
Yu J. et al. 2015 RP Gastric SGC7901 SGC7901 N/A
Location Method Result Regulation Validation Type Source
chr8:103382605-103382627 Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
High-throughput experiments (0 positive, 2 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Selbach M et al. 2008 MA Cervix HELA N/A 8hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays NEGATIVE INDIRECT TarBase 8.0
Selbach M et al. 2008 MA Cervix HELA N/A 32hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays NEGATIVE INDIRECT TarBase 8.0
RPIA hsa-let-7b-5p low: 2 high: 0 1 3 3 -
Low-throughput experiments (0 positive, 2 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Kiriakidou M et al. 2004 RP Brain MN1 MN1 N/A
Location Method Result Regulation Validation Type Source
chr2:88750120-88750142 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 6.0
Kiriakidou M et al. 2004 RP Cervix HELA HELA N/A
Location Method Result Regulation Validation Type Source
chr2:88750120-88750142 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 6.0
Other Databases
Publication Methods Tissue Cell line Tested cell line Exp. condition
Kiriakidou M et al. 2004 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
MAPK1 hsa-let-7b-5p low: 2 high: 0 1 2 2 -
Low-throughput experiments (0 positive, 2 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Fuqiong Chen et al. 2012 WB Mammary Gland MDAMB435 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Heart H9C2 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
GNPDA1 hsa-let-7b-5p low: 2 high: 0 1 1 1 -
Low-throughput experiments (2 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Xue Y et al. 2013 WB Cervix HELA N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot POSITIVE INDIRECT TarBase 7.0
Xue Y et al. 2013 RP Cervix HELA HEK293T Dual Luciferase Reporter Assay
Location Method Result Regulation Validation Type Source
UNKNOWN Luciferase Reporter Assay POSITIVE DIRECT TarBase 7.0
PIK3CA hsa-let-7b-5p low: 2 high: 0 1 2 2 0.715
Low-throughput experiments (1 positive, 1 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Fuqiong Chen et al. 2012 WB Mammary Gland MDAMB435 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot POSITIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Heart H9C2 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
LIN28A hsa-let-7b-5p low: 2 high: 0 1 2 2 -
Low-throughput experiments (2 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Kiriakidou M et al. 2004 RP Brain MN1 MN1 N/A
Location Method Result Regulation Validation Type Source
chr1:26427347-26427370 Luciferase Reporter Assay POSITIVE DIRECT TarBase 6.0
Kiriakidou M et al. 2004 RP Cervix HELA HELA N/A
Location Method Result Regulation Validation Type Source
chr1:26427347-26427370 Luciferase Reporter Assay POSITIVE DIRECT TarBase 6.0
AKT1 hsa-let-7b-5p low: 2 high: 0 1 2 2 -
Low-throughput experiments (0 positive, 2 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Fuqiong Chen et al. 2012 WB Mammary Gland MDAMB435 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
Fuqiong Chen et al. 2012 WB Heart H9C2 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
ACTG1 hsa-let-7b-5p low: 2 high: 0 1 2 2 0.466
Low-throughput experiments (0 positive, 2 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Kiriakidou M et al. 2004 RP Brain MN1 MN1 N/A
Location Method Result Regulation Validation Type Source
chr17:81510598-81510619 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 6.0
Kiriakidou M et al. 2004 RP Cervix HELA HELA N/A
Location Method Result Regulation Validation Type Source
chr17:81510598-81510619 Luciferase Reporter Assay NEGATIVE DIRECT TarBase 6.0
IGF1R hsa-let-7b-5p low: 1 high: 13 8 8 5 0.995
Low-throughput experiments (1 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Alajez Nehad M. et al. 2012 RP Pharynx FADU HEK293 N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
High-throughput experiments (13 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Grosswendt S et al. 2014 IP Pleura B lymphocyte N/A N/A
Location Method Result Regulation Validation Type Source
chr15:98960039-98960068 Chimeric fragments POSITIVE DIRECT TarBase 8.0
Grosswendt S et al. 2014 IP Kidney HEK293 N/A N/A
Location Method Result Regulation Validation Type Source
chr15:98960037-98960068 Chimeric fragments POSITIVE DIRECT TarBase 8.0
Xue Y et al. 2013 IP Cervix HELA N/A Hela cells were treated with control shRNA.
Location Method Result Regulation Validation Type Source
chr15:98960047-98960068 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Whisnant Adam W et al. 2013 IP Cervix TZMBL N/A N/A
Location Method Result Regulation Validation Type Source
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Whisnant Adam W et al. 2013 IP Cervix TZMBL N/A shRNAs against HIV-1
Location Method Result Regulation Validation Type Source
chr15:98960211-98960235 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr15:98707658-98707681 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Skalsky Rebecca L. et al. 2012 IP N/A EF3DAGO2 N/A N/A
Location Method Result Regulation Validation Type Source
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Sebastian Memczak et al. 2013 IP Kidney HEK293 N/A N/A
Location Method Result Regulation Validation Type Source
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Kishore S et al. 2011 IP Kidney HEK293 N/A mild MNase digestion
Location Method Result Regulation Validation Type Source
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Eva Gottwein et al. 2011 IP Pleura BC3 N/A N/A
Location Method Result Regulation Validation Type Source
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Eva Gottwein et al. 2011 IP Pleura BC1 N/A N/A
Location Method Result Regulation Validation Type Source
chr15:98960047-98960068 PAR-CLIP POSITIVE DIRECT TarBase 7.0
PRDM1 hsa-let-7b-5p low: 1 high: 5 6 5 4 -
Low-throughput experiments (1 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Kui Nie et al. 2010 RP Kidney HEK293T HEK293T N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
High-throughput experiments (4 positive, 1 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Grosswendt S et al. 2014 IP Pleura B lymphocyte N/A N/A
Location Method Result Regulation Validation Type Source
chr6:106099419-106099449 Chimeric fragments POSITIVE DIRECT TarBase 8.0
Selbach M et al. 2008 MA Cervix HELA N/A 8hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays NEGATIVE INDIRECT TarBase 8.0
Xue Y et al. 2013 IP Cervix HELA N/A Hela cells were treated with control shRNA.
Location Method Result Regulation Validation Type Source
chr6:106107417-106107436 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Haecker Irina et al. 2012 IP Bone Marrow BCBL1 N/A N/A
Location Method Result Regulation Validation Type Source
chr6:106107417-106107436 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Eva Gottwein et al. 2011 IP Pleura BC1 N/A N/A
Location Method Result Regulation Validation Type Source
chr6:106108798-106108818 PAR-CLIP POSITIVE DIRECT TarBase 7.0
CCND2 hsa-let-7b-5p low: 1 high: 11 7 7 5 0.875
Low-throughput experiments (1 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Alajez Nehad M. et al. 2012 RP Pharynx FADU HEK293 N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
High-throughput experiments (11 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Boudreau RL et al. 2014 IP Brain N/A N/A N/A
Location Method Result Regulation Validation Type Source
chr12:4302038-4302065 HITS-CLIP POSITIVE DIRECT TarBase 8.0
chr12:4302038-4302065 HITS-CLIP POSITIVE DIRECT TarBase 8.0
chr12:4302038-4302065 HITS-CLIP POSITIVE DIRECT TarBase 8.0
Skalsky Rebecca L. et al. 2012 IP N/A LCLBAC N/A N/A
Location Method Result Regulation Validation Type Source
chr12:4304904-4304928 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Skalsky Rebecca L. et al. 2012 IP N/A LCL35 N/A N/A
Location Method Result Regulation Validation Type Source
chr12:4304904-4304928 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:4301977-4301998 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Kishore S et al. 2011 IP Kidney HEK293 N/A mild MNase digestion
Location Method Result Regulation Validation Type Source
chr12:4304904-4304928 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:4301977-4301998 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Eva Gottwein et al. 2011 IP Pleura BC3 N/A N/A
Location Method Result Regulation Validation Type Source
chr12:4301977-4301998 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Eva Gottwein et al. 2011 IP Pleura BC1 N/A N/A
Location Method Result Regulation Validation Type Source
chr12:4304904-4304928 PAR-CLIP POSITIVE DIRECT TarBase 7.0
chr12:4302038-4302065 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Other Databases
Publication Methods Tissue Cell line Tested cell line Exp. condition
Charles D Johnson et al. 2007 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
Alajez Nehad M. et al. 2012 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
Valerie B Sampson et al. 2007 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
CCND1 hsa-let-7b-5p low: 1 high: 4 7 6 6 -
Low-throughput experiments (1 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Julia Schultz et al. 2008 RP Skin G361 N/A N/A
Location Method Result Regulation Validation Type Source
chr11:69651375-69654407 Luciferase Reporter Assay POSITIVE DIRECT TarBase 6.0
High-throughput experiments (4 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Whisnant Adam W et al. 2013 IP Cervix TZMBL N/A shRNAs against HIV-1
Location Method Result Regulation Validation Type Source
chr11:69653482-69653502 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Pillai MM et al. 2014 IP Mammary Gland BT474 N/A N/A
Location Method Result Regulation Validation Type Source
chr11:69653482-69653502 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Kishore S et al. 2011 IP Kidney HEK293 N/A mild MNase digestion
Location Method Result Regulation Validation Type Source
chr11:69653482-69653502 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Balakrishnan I et al. 2014 IP Bone Marrow HS5 N/A N/A
Location Method Result Regulation Validation Type Source
chr11:69653482-69653502 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Other Databases
Publication Methods Tissue Cell line Tested cell line Exp. condition
Chunnian Zhao et al. 2010 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
Whisnant Adam W et al. 2013 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
Julia Schultz et al. 2008 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
Guo Yong et al. 2013 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
EDN1 hsa-let-7b-5p low: 1 high: 5 5 5 4 0.993
Low-throughput experiments (1 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Tsai KW. et al. 2015 RP Stomach AGS HEK293T N/A
Location Method Result Regulation Validation Type Source
chr6:12296092-12297166 Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
High-throughput experiments (5 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Whisnant Adam W et al. 2013 IP Cervix TZMBL N/A shRNAs against HIV-1
Location Method Result Regulation Validation Type Source
chr6:12296624-12296646 PAR-CLIP POSITIVE DIRECT TarBase 7.0
Selbach M et al. 2008 MA Cervix HELA N/A 8hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays POSITIVE INDIRECT TarBase 8.0
Selbach M et al. 2008 MA Cervix HELA N/A 32hrs post-transfection, Overexpression
Location Method Result Regulation Validation Type Source
UNKNOWN Microarrays POSITIVE INDIRECT TarBase 8.0
Xue Y et al. 2013 IP Cervix HELA N/A Hela cells were treated with control shRNA.
Location Method Result Regulation Validation Type Source
chr6:12296624-12296646 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Pillai MM et al. 2014 IP Mammary Gland BT474 N/A N/A
Location Method Result Regulation Validation Type Source
chr6:12296624-12296646 HITS-CLIP POSITIVE DIRECT TarBase 7.0
Other Databases
Publication Methods Tissue Cell line Tested cell line Exp. condition
Whisnant Adam W et al. 2013 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
IGF2BP2 hsa-let-7b-5p low: 1 high: 2 3 3 3 -
Low-throughput experiments (1 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Alajez Nehad M. et al. 2012 RP Pharynx FADU HEK293 N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Luciferase Reporter Assay POSITIVE DIRECT TarBase 8.0
High-throughput experiments (2 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Selbach M et al. 2008 PR N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN pSILAC POSITIVE INDIRECT TarBase 6.0
Balakrishnan I et al. 2014 IP Bone Marrow HS5 N/A N/A
Location Method Result Regulation Validation Type Source
chr3:185644220-185644241 HITS-CLIP POSITIVE DIRECT TarBase 7.0
CCNA1 hsa-let-7b-5p low: 1 high: 0 1 2 2 -
Low-throughput experiments (1 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Julia Schultz et al. 2008 RP Skin G361 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Luciferase Reporter Assay POSITIVE DIRECT TarBase 6.0
Other Databases
Publication Methods Tissue Cell line Tested cell line Exp. condition
Julia Schultz et al. 2008 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase
NME1 hsa-let-7b-5p low: 1 high: 0 1 1 1 -
Low-throughput experiments (0 positive, 1 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Fuqiong Chen et al. 2012 WB Mammary Gland MDAMB435 N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Western Blot NEGATIVE INDIRECT TarBase 7.0
MT-ATP6 hsa-let-7b-5p low: 0 high: 6 3 4 3 -
High-throughput experiments (6 positive, 0 negative)
Publication Methods Tissue Cell line Tested cell line Exp. condition
Helwak Aleksandra et al. 2013 IP Kidney FLPIN_TREX_293 N/A N/A
Location Method Result Regulation Validation Type Source
chrMT:9070-9121 CLASH POSITIVE DIRECT TarBase 7.0
chrMT:8947-9022 CLASH POSITIVE DIRECT TarBase 7.0
chrMT:8905-8968 CLASH POSITIVE DIRECT TarBase 7.0
Grosswendt S et al. 2014 IP Kidney HEK293 N/A N/A
Location Method Result Regulation Validation Type Source
chrMT:8660-8695 Chimeric fragments POSITIVE DIRECT TarBase 8.0
Moore M et al. 2015 IP Liver HUH7.5 N/A N/A
Location Method Result Regulation Validation Type Source
chrMT:8454-8529 CLEAR-CLIP POSITIVE DIRECT TarBase 8.0
chrMT:8671-8746 CLEAR-CLIP POSITIVE DIRECT TarBase 8.0
Other Databases
Publication Methods Tissue Cell line Tested cell line Exp. condition
Helwak Aleksandra et al. 2013 O N/A N/A N/A N/A
Location Method Result Regulation Validation Type Source
UNKNOWN Other UNKNOWN UNKNOWN miRTarBase